Thursday, August 6, 2009

HHV-1 = predominantly oral - HHV-2 = predominantly genital

TypeSynonymSubfamilyPrimary Target CellPathophysiologySite of LatencyMeans of Spread
HHV-1Herpes simplex virus-1 (HSV-1)α (Alpha)MucoepithelialOral and/or genital herpes (predominantly orofacial), as well as other herpes simplex infectionsNeuronClose contact
HHV-2Herpes simplex virus-2 (HSV-2)αMucoepithelialOral and/or genital herpes (predominantly genital), as well as other herpes simplex infectionsNeuronClose contact (sexually transmitted disease)


There are eight distinct viruses in this family known to cause disease in humans